Short-term curative effect of external irradiation of 15Gy plus operation for bulky stage Ⅱ cervical carcinoma
AIM: To evaluate the curative effect of preoperation high-dose-rate external irradiation plus operation for bulky stage Ⅱ cervical carcinoma. METHODS: A retrospective review was performed of 30 patients with bulky stage Ⅱ cervical carcinoma treated by 5 Gy × 3D external irradiation before operation. Compared with 20 cases of bulky cervical cancer of the same stage only recepted radical hysterectomy. RESULTS: In the external irradiation group, the clinical complete remission (CR), partial remission (PR), stable diameter (SD) and progression disease (PD) were 3.3%, 73.3%, 23.3%, and 0, respectively. Incidence of radiotherapy complication was low. The subsequent surgery went well. Operation time and blood loss decreased significantly, post-operative complication as urinary retention was significantly lower than the only operation group. No significannt difference in high-risk pathology. CONCLUSION: 5 Gy/f × 3f external irradiation before operation can well diminute the tumor of bulky stage Ⅱ cervical carcinoma, lower incidence of complication, not to increase intraoperative and postoperative complications.