Comparison of clinical effect between etomidate and propofol in analgesic artificial abortion
AIM: To compare the clinical effect of etomidate and propofol used for analgesic artificial abortion. METHODS: Two hundred clinical volunteers of termination of 38-to-85-day pregnancy (ASA Ⅰ-Ⅱ grade) were randomly divided into 2 groups, with 100 subjects in each group. After 1 mg midazolam followed by 2 ug/kg fentanyl 1 min later, the subjects in group A received 2 mg/kg propofol and the subjects in group B received 0.2 mg/kg etomidate. The levels of MAP, HR and SpO2 were monitored and recorded at three time points during anesthesia, and the intraoperative analgesic effect, the postoperative recovery time and the occurrence rate of intravenous injection pain of the 2 groups were recorded. RESULTS: No significant differences were observed in the intraoperative analgesic effect and the postoperative recovery time between the 2 groups. The levels of MAP, HR and SpO2 in group A significantly declined (P ＜0.05) and the occurrence rate of intravenous injection pain in group A was notably higher than that in group B (P ＜ 0.05). CONCLUSION: Both etomidate and propofol are effective for analgesic artificial abortion. But etomidate has the advantages of stable blood hemodynamics and lower rate of intravenous injection pain.
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万方数据
维普
