首页|健康成人甲状腺结节4306例患病情况调查

健康成人甲状腺结节4306例患病情况调查

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目的:了解健康人群中甲状腺结节的患病率、结节特征及其与年龄、性别等的关系.方法:对既往无甲状腺手术史的健康成人4306例行甲状腺超声检测并测定促甲状腺激素(TSH)及甲状腺球蛋白抗体(TGAb).结果:在无甲状腺手术史的健康人群4306例中,共发现甲状腺结节675例,检出率15.7%.甲状腺结节患病率随年龄增长呈增加趋势,女性在31~60岁组中结节患病率高于男性.不同TSH及TGAb水平下,甲状腺结节检出率无明显差异.检出结节以直径小于1cm的小结节(77%)和单发结节(70%)为主.随年龄增加,大结节及多发结节所占比例增加,但结节大小、数目与性别无关.对70例直径大于1 cm的结节患者行甲状腺细针穿刺,其中3例诊断为甲状腺癌,经手术证实为甲状腺乳头状癌.结论:甲状腺结节在人群中患病率较高,多数为触不到的小结节,女性多于男性,结节患病率随年龄增长而增加,恶性率低.
Prevalence of thyroid nodules in 4306 healthy adult population
AIM: To evaluate the prevalence and characteristics of thyroid nodules in 4306 healthy adult population. METHODS: Included in the study were 4306 adults without thyroid surgery history and ultrasonographic examination of thyroid gland and measurement of serum thyrotropin (TSH) and thyroglobulin antibody (TGAb) were conducted. RESULTS: Thyroid nodules were detectable in 675 subjects (15.7%) by ultrasonographic examination. The thyroid nodule prevalence increased with the increasing of age. The nodule prevalence in women aged between 31-60 years was higher than that in men of the same age group. No evidence showed that the nodule prevalence was relevant with TSH and TGAb levels. Most nodules were smaller than 1 cm (77%) and solitary (70%). Larger and multiple nodules were more common in the elderly, but no obvious difference was observed in the size and number of thyroid nodules between men and women. Fine-needle aspiration biopsy was applied to 70 subjects with thyroid nodules bigger than 1 cm. Three patients were diagnosed as having thyroid cancer and were confirmed historically after surgery. CONCLUSION: The prevalence of thyroid nodule is high even in healthy adults, and it is more common in the elderly and women. Most of the nodules are impalpable and benign.

thyroid noduleprevalenceultrasound

刘星君、滕卫平、施秉银、魏丹国、段培真、李丽莉、路万虹、樊萍、李娟

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西安交通大学医学院第一附属医院内分泌内科,陕西,西安,710061

中国医科大学附属第一医院,辽宁,沈阳,110001

长庆石油勘探局建设工程总公司卫生所,陕西,西安,710000

西安邮电学院卫生所,陕西,西安,710000

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甲状腺结节 患病率 超声

国家科技攻关计划

2004BA720A30

2009

第四军医大学学报
第四军医大学

第四军医大学学报

CSTPCDCSCD北大核心
影响因子:0.599
ISSN:1000-2790
年,卷(期):2009.30(19)
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