Changes of functional connectivity of ACC in resting state during slee pdeprivation: An fMRI study
AIM: To explore the impact of total sleep deprivation (TSD) on functional connectivity of ACC in resting state. METHODS: Healthy young men (n = 14) completed rest fMRI scan before and after the 36-TSD. fMRI scans were carried out in these subjects 3 weeks apart. RESULTS: TSD induced positive and negative functional connectivity compared with that after the normal sleep. The activated areas with positive FC include the PC, etc. and with negative FC in thalamus. CONCLUSION: The maintaining of awareness is supported by thalamus during rest state. The strengthening functional connectivity of default network in sleep deprivation reflects the consistent changes in the system, which may be related to the impacting function of attention and inhibition system and the decline of wakefulness.
total sleep deprivationfunctional magnetic resonance imaginganterior cingulated cortexfunctional connectivity
NETL
NSTL
万方数据
维普
