Intervention effect of Jinkuishenqiwan on the kidney-yang deficiency in rats
AIM: To explore the ability and mechanism of Jinkuishenqiwan to inhibit the spemratgoenic arrest infertile. METHODS: One hundred mature male rats were divided into 5 groups randomly: Blank group, model group, treated group with high dosage Jinkuishenqiwan, with middle dosage Jinkuishenqiwan, with low dosage Jinkuishenqiwan. Except the normal group, the others were made into model of kidney-yang deficiency by injecting hydrocortisone. simultaneityly the treatment of Jinkuishenqiwan also was irrigated into the stomachs of the high, middle and low group. After 30 d, the concentration of testosterone, the status and movement percent of sperm were examined: the microstructure of textile was observed under optical microscope. RESULTS: All those datum had some improving tendency after irrigated Jinkuishenqiwan compared with the model group. CONCLUSION: It is indicated that Jinkuishenqiwan exerts a certain therapeutic effect on the kidney-yang deficiency in rats.
Jinkuishenqiwanmodel of kidney-yang deficiencyspermatogenic arresttestosterone