Immunohistochemical expression of gonadotrop in releasing hormone in pancreatic cancer
AIM: To explore the immunohistochemical expression and clinical significance of GnRH in pancreatic cancer. METHODS: GnRH was detected in 46 pancreatic cancer tissues by immunohistochemical streptavidin-peroxidase (SP) method, including 20 cases of highly differentiated pancreatic cancer tissues, 16 cases of moderately differentiated pancreatic cancer tissues, and 10 cases of poorly differentiated pancreatic cancer tissues. RESULTS: GnRH is located in membrance and cytoplasm of pancreatic cancer cells. The expression rate of GnRH in highly differentiated pancreatic cancer tissues is 78.55%, higher than that in moderately (59.31%) and poorly differentiated (50%) pancreatic cancer tissues, which shows that the more difference of pancreatic cancer, the higher expression of GnRH. CONCLUSION: The expression levels of GnRH are related with the malignant degree of pancreatic cancer, and GnRH may be involved in the occurrence and development of pancreatic cancer.
NETL
NSTL
万方数据
维普
