摘要
目的:考察静脉注射曲马多在预防小儿全麻苏醒期躁动的作用.方法:选择40例择期在全麻下行扁桃体和(或)腺样体摘除术的小儿,随机分为曲马多组和对照组.术中连续监测无创血压、心电图、心率、血氧饱和度.记录手术时间、麻醉时间、拔管时间并由评估拔管前两组患儿的Comfort评分.结果:两组在手术时间、麻醉时间、拔管时间、术后低氧血症、恶心呕吐发生率均没有统计学差异.Comfort评分:两组患者在镇静满意率及镇静不足率两项比较中有统计学差异(P<0.05或P<0.01);躁动评分:两组患者中无或轻度躁动的比率及重度躁动的比率分别有统计学差异(P<0.05).结论:在小儿扁桃体和(或)腺样体摘除术前静注曲马多,可获得苏醒期良好的镇静镇痛效果,减少了拔管期的躁动.同时,不影响拔管时间,不增加术后低氧血症、恶心呕吐、反流误吸等不良反应发生率.
Abstract
AIM: To evaluate the preventive effect of tramadol on restlessness during palinesthesia in children. METHODS: Forty children undergong selective tonsillectomy and(or) adenoidectomy were included in the study and allocated randomly into tramadol group and control group. Arterial pressure, electrocardiogram, heart rate, peripheral oxygen saturation were monitored continuously during the operation, record the surgery time, anesthesia time, extubation time. At the time of palinesthesia, a blind observer accessed the Comfort score before extubation. RESULTS: There was no significant difference among the surgery time, anesthesia time, extubation time, postoperative hypoxemia, nausea and vomiting in two group. According to Comfort score, the satisfaction rate and the rate of inadequate sedation was significant different between the two group(P ＜ 0.05 or 0.01). According to the restlessness score: The rate of no or mild restlessness and the rate of severe restlessness was significant different between the 2 group(P ＜ 0.05). CONCLUSION: The preventive function of tramadol can make the favorable sedation effect during palinesthesia and decrease the restlessness at the time of extubation in children undergoing tonsillectomy and (or) adenoidectomy surgery, meanwhile, tramadol didn't prolong the extubation time or increase the rate of the postoperative hypoxemia, nausea and vomiting.
NETL
NSTL
维普
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