Clinical characteristics of dogs after open abdominal injury and seawater immersion induced acute heart failure
AIM:To observe the clinical characteristics of dogs after open abdominal injury and seawater immersion induced acute heart failure.METHODS:Adult mongrel dogs as experimental animals were randomly divided into open abdominal injury+ seawater immersion group(A group n=8)and simple open abdominal injury group(B group n=8).To observe experimental animals caused by open abdominal injury before and after,and the seawater immersion after 2 h the water at different time points salvage cardiac rhythm,heart rate(HR),systolic pressure,diastolic pressure,mean arterial pressure(MAP),pulmonary wedge pressure(PAWP),central venous pressure(CVP),cardiac output(CO),cardiac index(CI),B-type brain natriuretic peptide(BNP),cardiac enzymes,partial pressure of oxygen and other relevant dimensions.On the injury before and after injury 4 h had ultrasonic cardiogram to measure LVEDV,LVESV,SV,LVEF.RESULTS:A group in the post-immersion heart rate,systolic pressure,diastolic pressure,mean arterial pressure,central venous pressure decreased.To 2 h,the pulmonary artery wedge pressure＞18 mmHg,cardiac output to reduce the 30% pre-injury,cardiac index,LVEDV,LVESV,SV,LVEF than those in group B reduced(P＜0.05),creatine kinase(CK),ereatine kinase isoenzyme(CK-MB),BNP than those in B group was significantly higher(P＜0.05).CONCLUSION:The dogs after open abdominal injury with seawater immersion expressed the characteristics of acute heart failure.
open abdominal injury,dogseawater,immersionacute heart failureclinical characteristics
NETL
NSTL
万方数据
维普
