Effects of the cactus pear juice and its polysaccharide extract on the experiment hyperlipemia and lipid peroxidation
AIM:To explore the effect of the cactus pear juice and its polysaccharide extract on the experiment hyperlipemia and lipid peroxidation.METHODS:According to the serum TC level,10 of 80 healthy male SD rat were randomly selected as control group which raised by basic animal feeds.The others were raised by hyper-fatty animal feeds for 3 weeks in order to established the hyperlipemia rat model.Seventy rats were divided into 7 groups randomly according to the serum TC(10/group):model group,low cactus pear juice group,middle cactus pear juice group,high cactus pear juice group,low polysaccharide group,high polysaccharide group,and lovastatin group.Continuing feeding hyper-fatty animal feeds,different doses were given separarely.RESULTS:The level of the serum TC,TG and LDL-C of rats raised by the hyper-fatty animal feeds for three weeks increased significantly(P＜0.01),while the level of the HDL-C decreased significantly(P＜0.05).When compared to the model group,the levels of the TC,TG,LDL-C and apoB decreased significantly(P＜0.01 or P＜0.05)in each group,while the level of the HDL-C increased significantly(P＜0.05)in high polysaccharide group and lovastatin group.The level of the apoA I increased without significant difference(P＞0.05).The level of the SOD increased significantly(P＜0.05 or P＜0.01)in the middle cactus pear juice group,high cactus pear juice group,low polysaccharide group,high polysaccharide group and lovastatin group 3 weeks later after administered.The level of the MDA decreased significantly(P＜0.05 or P＜0.01)in each group.CONCLUSION:The cactus pear juice and its polysaccharide have apparente effects on decreasing blood fat and antioxygen.We should study further into its active constituent and its mechanism.
NETL
NSTL
万方数据
维普
