目的:探讨应用Inoue球囊经皮肺动脉瓣成形术(PBPV)治疗成人肺动脉瓣狭窄(PVS)的临床疗效.方法:成人PVS患者56例,采用PBPV进行治疗,并以超声多普勒评价其疗效.结果:56例行PBPV患者术后即刻右心室收缩压由(103.4±27.2)mmHg(1 mmHg=0.133 kPa)降至(49.5±17.6)mmHg(P＜0.01),右房压由(17.2±5.5)mmHg降至(9.2±4.4)mmHg(P＜0.01),肺动脉压由(14.8±3.2)mmHg升至(22.1±5.3)mmHg(P＜0.05),肺动脉与右心室跨瓣压差(△P)由(78.2±26.1)mm Hg降至(22.8±12.4)mmHg(P＜0.01).多普勒超声随访:术后3 mo △P较术后即刻进一步显著下降(P＜0.05).结论:INONUE球囊PBPV治疗成人PVS安全有效.
A clinical analysis of percutaneous balloon pulmonary valvuloplasty with inoue-balloon for pulmonary valve stenosis in adults
AIM:To evaluate the clinical efficacy of percutaneous balloon pulmonary valvuloplasty(PBPV)with inoue-balloon for pulmonary valve stenosis(PVS)in adults.METHODS:The 56 cases with PVS were adopted by PBPV and the therapeutic results were evaluated by echocardiography.RESULTS:The mean systolic pressure of right ventricule decreased from(103.4±27.2)to(49.5±17.6)mmHg(P＜0.01);the mean pressure of right atrium from(17.2±5.5)to(9.2±4.4)mmHg(P＜0.05);the mean pressure of pulmonary artery increased from (14.8±3.2)to(22.1±5.3)mmHg(P＜0.05);the pressure gradient between right ventricule and pulmonary artery decreased from(78.2±26.1)to(22.8±12.4)mmHg(P＜0.01)just after PBPV in 56 patients.The pressure gradient between right vemriele and pulmonary continues to decrease(P＜0.05)after 3 months.CONCLUSION:Percutaneous inoue ballon dilation for pulmonary valve stenosis in adults is effective and safe.
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