首页|贝达飞微生态制剂治疗小儿肺炎继发腹泻的疗效观察及相关因素分析

贝达飞微生态制剂治疗小儿肺炎继发腹泻的疗效观察及相关因素分析

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目的:探讨小儿肺炎继发腹泻的危险因素及采用贝达飞微生态制剂对其治疗的临床效果.方法:347例肺炎患儿为研究对象,对小儿肺炎继发腹泻相关因素进行Logistic回归分析,筛选小儿肺炎继发腹泻的危险因素;110例肺炎继发腹泻患儿随机分为治疗组和对照组,治疗组采用贝达飞微生态制剂治疗,对照组采用乳酶生片治疗,治疗结束后评价临床疗效.结果:①单因素分析显示:患儿年龄、住院天数、住院后有无侵入操作、微生态制剂的应用、居住地、病情严重程度、血中性粒细胞计数、血红蛋白数量、激素应用与小儿肺炎继发腹泻有关.非条件Logistic多因素回归分析筛选出2个危险因素:患儿年龄小、人院后有侵入性操作;1个保护因素:微生态制剂的应用.②治疗组临床疗效总有效率为92.6%,显著高于对照组(61.4%),相比较有统计学差异(P<0.05).结论:患儿年龄小、住院期间有进行侵入性操作为小儿肺炎继发腹泻的危险因素;采用贝达飞微生态制剂治疗小儿肺炎继发腹泻疗效确切,值得临床上推广应用.
Clinical effect of beidafei probiotics treatment on secondary diarrhea of children pneumonia and analysis of related factors
AIM:To investigate the risk factors of secondary diarrhea of children pneumonia(SDCP)and clinical effect of beidafeiprobiotics.METHODS:347 eases of children pneumonia were studied,for children with pneumonia secondary to diarrhearelated factors Logistic regression analysis;110 cases of SDCP were randomly divided into treatment group and control group,the treatment group was given beidafei probiotics treatment,the control group was given lactasin tablets treatment.After treatment the clinical effect Was evaluated.RESULTS:①ANOVA indicated:children age,hospital days,whether invasive operation after hospitalization,application of probiotics,residence place,severity of disease,blood neutrophil count,hemo~obin quantity,the use of hormone were related with SDCP.Nonconditional multiplicity logistic regression model analysis showed that younger children and during hospitalization for invasive procedures were risk factors of SDCP.The application of probiotics was an independent protective factor of SDCP.②The total effective rate of the treatment group was 92.6%,significantly higher than that of the control group(61.4%),the difference was significant(P<0.05).CONCLUSION:The younger children and during hospitalization for invasive procedures were risk factors of SDCP.The clinical effect for beidafei probiotics treatment of SDCP is curative,which is worth clinical application.

secondary diarrhea of children pneumoniarisk factorsbeidafei probioticschildren

刘朝宙、徐明、周远大、何海霞

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湖南省儿童医院感染科,湖南,长沙,410007

重庆医科大学附属北碚医院药剂科,重庆,400700

重庆医科大学临床学院临床药理研究室,重庆,400016

肺炎 继发腹泻 贝达飞微生态制剂 儿童

重庆市自然科学基金重点项目重庆市自然科学基金重点项目

渝科发字第[2006]24号CSTC2006EB5030

2009

第四军医大学学报
第四军医大学

第四军医大学学报

CSTPCDCSCD北大核心
影响因子:0.599
ISSN:1000-2790
年,卷(期):2009.30(21)
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