Non-invasive positive pressure ventilation treatment of acute exacerbations of chronic obstructive pulmonary disease and respiratory failure type Ⅱ of efficacy
AIM:To observe the non-invasive positive pressure ventilation(NIPPV)for chronic obstructive pulmonary disease (COPD)and acute exacerbation of type Ⅱ respiratory failure.METHODS:Thirty-nine patients with acute exacerbation of COPD and respiratory failure in patients with type Ⅱ were divided into treatment and control groups were compared on admission and admission to hospital 2,24,72 h arterial blood gas analysis,the number of patients required endotracheal intubation.RESULTS:The treatment group in the application of NIPPV after 2,24,72 h in the PH value of blood gas analysis,PaO_2 higher than at admission were significantly different(P<0.05),PaCO_2 on admission than in the 72 h difference was significant(P<0.05).The treatment group and control group after PH in the treatment of 2 h values,PaCO_2 difference was not statistically significant,and PaO_2 were significantly different(P<0.05);treatment group and control group in the treatment of 24,72 h after the PH value,PaO_2,PaCO_2 difference was significant(P<0.05);treatment group intubation rate was 5%in the control group intubation rate was 26.3%,the difference was significant(P<0.05).CONCLUSION:NIPPV treatment of acute exacerbations of COPD and respiratory failure type Ⅱ sure,fewer adverse reactions.The control of their indications and contraindications as soon as possible after the use of NIPPV,in order to get to rest and recuperate in patients with respiratory muscle,reduce the rate ofendotracheal intubation to prevent further aggravate the condition.