首页|无创正压通气治疗慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭的疗效观察

无创正压通气治疗慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭的疗效观察

扫码查看
目的:观察无创正压通气(NIPPV)治疗慢性阻塞性肺疾病(COPD)急性加重期并Ⅱ型呼吸衰竭的疗效.方法:39例COPD急性加重期并Ⅱ型呼吸衰竭患者分为治疗组和对照组,比较两组入院时及入院后2,24,72 h动脉血气分析结果、需气管插管的患者人数.结果:治疗组在应用NIPPV后2,24,72 h血气分析中pH值、PaO_2较入院时差异有统计学(P<0.05),PaCO_2在72 h较入院时差异有统计学意义(P<0.05).治疗组和对照组在治疗2 h后的pH值、PaCO_2差异无统计学意义,而PaO_2有统计学差异(P<0.05);治疗组和对照组在治疗24,72 h后pH值、PaO_2,PaCO_2差别均有统计学意义(P<0.05);治疗组插管率是5%,对照组插管率是26.3%,两者差异有统计学意义(P<0.05).结论:NIPPV治疗COPD急性加重期并Ⅱ型呼吸衰竭疗效肯定,不良反应较少.在掌握其适应证和禁忌证后可尽早使用NIPPV,以便使患者呼吸肌得到休息恢复,减少气管插管率,避免病情进一步加重.
Non-invasive positive pressure ventilation treatment of acute exacerbations of chronic obstructive pulmonary disease and respiratory failure type Ⅱ of efficacy
AIM:To observe the non-invasive positive pressure ventilation(NIPPV)for chronic obstructive pulmonary disease (COPD)and acute exacerbation of type Ⅱ respiratory failure.METHODS:Thirty-nine patients with acute exacerbation of COPD and respiratory failure in patients with type Ⅱ were divided into treatment and control groups were compared on admission and admission to hospital 2,24,72 h arterial blood gas analysis,the number of patients required endotracheal intubation.RESULTS:The treatment group in the application of NIPPV after 2,24,72 h in the PH value of blood gas analysis,PaO_2 higher than at admission were significantly different(P<0.05),PaCO_2 on admission than in the 72 h difference was significant(P<0.05).The treatment group and control group after PH in the treatment of 2 h values,PaCO_2 difference was not statistically significant,and PaO_2 were significantly different(P<0.05);treatment group and control group in the treatment of 24,72 h after the PH value,PaO_2,PaCO_2 difference was significant(P<0.05);treatment group intubation rate was 5%in the control group intubation rate was 26.3%,the difference was significant(P<0.05).CONCLUSION:NIPPV treatment of acute exacerbations of COPD and respiratory failure type Ⅱ sure,fewer adverse reactions.The control of their indications and contraindications as soon as possible after the use of NIPPV,in order to get to rest and recuperate in patients with respiratory muscle,reduce the rate ofendotracheal intubation to prevent further aggravate the condition.

non-invasive positive pressure ventilationchronic obstructive pulmonary diseaserespiratory failure

张志强、马海英、杨艳荣

展开 >

新乡医学院第一附属医院呼吸科,河南,卫辉,453100

新乡医学院第一附属医院心外科,河南,卫辉,453100

无创正压通气 慢性阻塞性肺疾病 呼吸衰竭

2009

第四军医大学学报
第四军医大学

第四军医大学学报

CSTPCDCSCD北大核心
影响因子:0.599
ISSN:1000-2790
年,卷(期):2009.30(21)
  • 1
  • 4