Detection of serum food-specific IgG in several common chronic diseases in children
AIM: To investigate the main types of food allergen in children in Urumqi and provide a new instruction for therapy and prevention of food intolerance in children. METHODS: A total of 87 patients were enrolled, whose age ranged from 4 months to 14 years old. In this study 14 food-specific IgG antibodies in serum were detected by ELISA assay and all the food allergens included in this test were milk, egg, wheat, rice, soybean, shrimp, crab, tomato, beef, corn, codfish, mushroom, chicken and pork. RESULTS: The positive rates of the 14 food allergens,listed from high to low, were milk(56.32% ), egg(44.83% ), wheat(32.18% ), rice( 13. 79% ) , soybean (13. 79% ), shrimp ( 11. 50% ) , crab (9.20% ) , tomato(8.04% ), beef(5.75% ) , corn(5.75 ) , cod-fish(3.45), mushroom (3. 45), chicken (2. 30) , pork(l. 15%). Except that the positive rate of shrimp was found higher in males than in females, the positive rates of the other 13 food were not significantly different in sex. CONCLUSION: Milk, egg and wheat are the main types of food allergen in urumqi and the positive rate of food intorlerance in children was high. Detection of food-specific IgG in serum was significant for therapy and prevention for common chronic diseases in children.