Comparative study on treatment for hepatocellular carcinoma by different interventional modes and the factor affecting the prognosis
AIM:To evaluate the efficiency of different interventional mode in treating primary hepatocellular carcinoma and the factor affecting the prognosis. METHODS:193 cases with hepatocellular carcinoma from 2002 to 2006 were undertaken transcatheter arterial chemoembolization(TACE group, n = 56),radiofrequency ablation(RFA group, n = 52), TACE and RFA (TACE + RFA group, n = 45), RFA and TACE(RFA + TACE group,n = 40). The Cox's regression analysis model was used to analyse the factors affecting the prognosis. RESULTS:In the 4 groups,TACE + RFA group obtained the best curative effect, the highest survival rate and the longest middle life span;The best achievement on the loss degree of AFP value also happened in TACE + RFA group. Cox regression simplex actor analysis display significantly influential factors such as liver functional classification, carcinoma lock, tumour diminution rate, treatment and AFP value of post-treatment. Multiplicity display that carcinoma lock and TACE + RFA treatment two factors make sense to prognosis.CONCLUSION:Of the 3 groups, TACE + RFA method have better curative effect than with either TACE or RFA. The impact of intervention in the treatment of liver cancer prognosis is an important factor:the availability of tumor thrombus and TACE + RFA treatment.
NETL
NSTL
万方数据
维普
