摘要
目的:探讨急性冠状动脉综合征(ACS)患者的心电图U波倒置形态改变与冠脉病变的关系.方法:选择2005-12/2009-05我院经冠状动脉造影(CAG)确诊的ACS患者69例,所有患者均进行心电图和CAG检查,记录CAG结果和心电图U波倒置形态改变并进行对比分析.结果:本组69例ACS患者中U波倒置的患者30例,尤U波倒置的患者39例.U波倒置患者UA和STEMI的患病率明显低于无U波倒置患者(P<0.05),而NSTEMI的患病率则明显高于无U波倒置患者;U波倒置患者与非U波倒置患者相比,E值下降、A值升高、E/A下降、EF值下降,且均有统计学差异(P<0.05);冠脉造影结果显示,U波倒置患者与无U波倒置患者在回旋支和右冠脉的发生率相似;左主干和左前降支的发生率比较,U波倒置患者明显高于无U波倒置患者(P<0.05);U波倒置患者双支、三支病变发生率明显高于无U波倒置患者,单支病变发生率明显低于无U波倒置患者(P<0.05);U波倒置患者冠脉病,变狭窄程度明显高于无U波倒置患者(P<0.05);U波倒置患者的冠脉病变表面形态以复杂病变为主,而无U波倒置患者以简单病变为主,两者比较差异具有统计学意义(P<0.05);分析30例U波倒置的ACS患者的U波倒置深度与冠脉病变的关系显示:冠脉病变的支数和狭窄程度与U波倒置的深度密切相关(P<0.05).结论:ACS患者的心电图U波对判断患者病情及预后有重要临床价值.
Abstract
AIM:To investigate the relation between U wave inversion and coronary angiography(CAG)of acute coronary syndrome.METHODS:Sixty-nine patients who were diagnosed with ACS by CAG from December 2005 to May 2009.All patents underwent CAG and electrocardiographic examination.The result of CAG and the change of ECG were recorded,compared and analyzed.RESULTS:There were 30 cases of U wave inversion and 39 cases of U wave non-inversion.The incidence of UA and STEMI were higher in the U wave inversion than in U wave non-inversion (P<0.05).The left ventricular systolic function and diastolic function was also higher in the U wave inversion.The incidence of the left main coronary artery(LM)and the left anterior descending coronary artery(LAD)was higher in U wave inversion than in U wave non-inversion(P<0.05).Furthermore,the incidence of two-vessel and three-vessel coronary arteries and the stenosis of coronary artery in U wave inversion were higher than that in U wave non-inversion(P<0.05).The narrowing characteristics of coronary artery in U wave inversion were more likely to be complex lesion(P<0.05).The depth of U wave in 30 cases with U wave inversion was closely related to the number of vessel and the stenosis of coronary artery(P<0.05).CONCLUSION:U wave inversion was a predictor of the prognosis of severe degree of acute coronary syndrome.