AIM:To prepare curcumin encapsulated lipsome with high encapsulation rate and good stability,in order to enhance the biological availability.METHODS:First,analysis a lot of literature reports and do a prepared experiment.Then,through the single factor experiment and orthogonal experiment,choose the best prepared craft.At last,prepared freeze-dried lipsome of curcumin.RESULTS:The encapsulation rate of curcuvain lipsome prepared by the method of ethanal injection technique is 46.69%,solubility of drugs and stability are significantly increased as well.CONCLUSION:It is feasible to select lipsome as the drug carrier ofcurcumin by the method of ethanal injection.The preparation process of ethanol injection is simple and apt to control.The new form of prepared drug Call improve bioavailability of curcumin.
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