首页|重庆市饥荒时期出生人群代谢综合征现时患病情况调查

重庆市饥荒时期出生人群代谢综合征现时患病情况调查

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目的:代谢综合征(MS)是重大的社会问题,通过调查重庆市1959/1961年出生人群MS患病状况,了解历经饥荒的中国人早年营养状况与成年后患MS的关系,为采取有效的预防和控制措施提供依据.方法:采自2005/2008年上半年重庆医科大学附属第一医院体榆中心体检资料,选取1959/1961年出生的3482例体检人群作为研究对象进行整群抽样,运用SAS9.1分析MS发生情况.结果:重庆市饥荒年出生人群中MS患病率为11.52%,其中男性16.41%,女性3.78%.与同样采用CDS诊断标准、同样出生于饥荒年年龄段的我国2002年MS调查结果(男性患病率为10.06%,女性患病率为3.2%)相比,明显高于全国水平.本调查男性患病率高于女性,差异有统计学意义.MS诊断标准中各单一指标均未超标的只占总人数的1/3左右(31.85%),其中男性462例,占总人数的13.27%;女性647例,占总人数的18.58%.代谢异常(MA)的人群中诊断指标:1种异常占35.07%、2种异常占21.57%、3种及以上异常的占11.52%,对MS的危险因素进行单因素及多因素的Logistic回归分析显示高危因素,除超重和肥胖的影响外,其他前三位因素依次为高三酰甘油、高舒张压和高收缩压.结论:饥荒造成的机体早期营养不良可能与成年后患慢性病有关.MA严重,且各独立的慢性病组分对MS患病均有影响.为了有效降低社会负担,提高居民营养知识水平和提倡健康生活理念迫在眉睫.
Cross-sectional investigation of metabolic syndrome in persons born in the famine period in Chongqing City
AIM:To investigate the status of this syndrome among the people who were born between 1959 and 1961 in Chongqing,and understand the relationship between the early-life nutritional status of the Chinese who had experienced the"Great Leap Forward"famine and the MS in their adulthoods,and then provide the reference for effective precautions and control measures.METHODS:3482 cases born from 1959 to 1961 were sampled from the Personal Medical Examination Database(data between 2005 and first half of 2008)of the Medical Examination Center in the First Affiliated Hospital of Chongqing Medical University,and SAS version 9.1 was used to analyze the occurrence of MS.RESULTS:The MS morbidity of the people in Chongqing who were born in the famine period is 11.52%,and the morbidity of male is 16.41% and 3.78%for the female.Compared with the results(male is 10.06%,for female is 3.2%)of the 2002 nationwide survey carded out with the same CDS diagnostic criteria and also from the same age group,the results of this study are significantly higher than the national average.the morbidity of male is higher than that of female,and this difference is meaningful to statistics.Only about one third(31.85%)of the cases didn't surpass any single index of the MS diagnostic criteria,among them,462 cases are male and account for 13.27%;647 cases are female and account for 18.58%.Diagnostic indexes of metabolic abnormality(MA)among people;cases with one kind of abnormalities account for 35.07%;cases with two kinds of abnormalities account for 21.57%;11.52% of the cases have three or more abnormalities.The single-factor and multi-factors Logistic Regression Analysis on the MS showed that the top three risk factors,besides overweight and obesity,are high triaylglycerol,high diastolic blood pressure and high systolic blood pressure.CONCLUSION:The early malnutrition in the famine period may result in chronic diseases in adulthood.Severe MA and various independent chronic diseases also influenced the MS morbidity.In order to release the social burden,improving citizens'knowledge of nutrition and promoting a healthy living concept are imminent.

earlier period of lifemalnutritionchronic diseasemetabolic syndromecross-sectional investigation

关蕴良、王永红、李廷玉、刘友学、赵勇

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重庆医科大学公共卫生学院营养与食品卫生学教研室,重庆400016

重庆医科大学儿童医院重庆市儿童营养研究中心,重庆,400014

重庆医科大学学报编辑部,重庆,400016

重庆医科大学一院体检中心,重庆,400016

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生命早期 营养不良 慢性病 代谢综合征 现况调查

教育部人文社会科学研究青年基金

08JC840021

2009

第四军医大学学报
第四军医大学

第四军医大学学报

CSTPCDCSCD北大核心
影响因子:0.599
ISSN:1000-2790
年,卷(期):2009.30(24)
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