To predict the vibration response of buildings along subway lines quickly and reasonably,a building structural system is decomposed into two parts,namely,a propagation structure and a response structure,based on the theory of mechanical mobility.The bearing structure is assumed to be a beam element model,and the slab structure is considered a plate element model.The mobility formula and the corresponding matrix expressions for each unit system are derived,and a train-induced structural vibration response model is constructed.The reliability and accuracy of the model are validated through on-site testing,showing that the predicted structural responses align well with measured vibrations in both time and frequency domains.In the frequency domain,the maximum error of the center frequencies of each 1/3 octave band does not exceed 5 dB,indicating that the proposed train-induced structural vibration response model can quickly and effectively predict the structural vibration response and that the outcomes can provide theoretical support for vibration prediction along subway lines.