The experiment was designed as 10-day-old juvenile Monopterus albus [weight (0.030±0.001) g] were fed with aquatic worms to 30-day-old(d30), 40-day-old(d40) and 50-day-old(d50) to study the effects of different starting points of weaning on the growth and survival rate of juvenile Monopterus albus.The weaning process was followed by feeding powdered compound feed,0.6, 1.0, 1.5 mm pellet feed for ten days each, for 40 days.After the weaning process was completed,each group of M.albus was fed with 1.5 mm pellet feed until they were 120 days of age.The results were as follows:With the increase in age and the change in food, the survival rate of each group remained above 97.00% and the difference was not significant.The weight of each group showed an upward trend;the weight gain rate(WGR), specific growth rate (SGR) and feed conversion ratio(FCR) of each group showed a downward trend.During 90~120 days of age, the weight of d50 group was significantly higher than that of the other two groups; the WGR and SGR of d50 group were higher than those of d40 group but not significant, and the two groups were significantly higher than the d30 group.During the experiment,the feed cost of each group was significantly different, among which the d50 group was the largest(19.69±0.52 ) yuan / kg, the d40 group was(16.81±0.41 ) yuan / kg and the d30 group was the most petite(13.49±0.40 ) yuan / kg.The WGR and SGR of each group decreased significantly in the stage of changing from aquatic worms to powdered compound feed,and increased after adjustin from powdery compound feed to 0.6 mm pellet feed.In the d30 group, the growth performance decreased when the 0.6 mm pellet feed was converted to 1.0 mm pellet feed( 50~60 days old ) and the 1.5 mm pellet feed stage (70~80 days old ) was completed, and the SGR decreased significantly.The above results show that early weaning will affect the next growth performance of the M.albus, and the appropriate delay of the weaning time will increase the subsequent growth performance of the M.albus.In summary, the results indicated that the time for the juvenile M.albus, which feeds with the aquatic worms as the opening food to weaning the powdered compound feed, is 40 to 50 days of age.