Progress on the Molecular Mechanisms of Infectious Bursal Disease Virus Infection and Replication
Infectious bursal disease is an acute,highly contagious,immunosuppressive avian disease caused by infectious bursal disease virus which has resulted in significant economic losses to the poultry industry and garnered widespread attention.Currently,numerous researchers have conducted extensive investiga-tions on IBDV and have discovered that the molecular mechanism underlying IBDV infection and replica-tion is highly intricate.This article comprehensively examines the involvement of IBDV proteins,host pro-teins,and their interactions in the processes of infection and replication.Additionally,it explores the recep-tor binding sites of IBDV in host cells,as well as miRNAs,lncRNAs,and circRNAs that regulate host cyto-kines and interferon responses,cell apoptosis,following IBDV infection while influencing virus propagation.The findings presented herein serve as a valuable reference for further research on IBDV pathogenesis and contribute to its prevention and control.
万方数据
维普
