首页|Effect of changing the proportion of C16∶0 and cis-9 C18∶1 in fat supplements on rumen fermentation,glucose and lipid metabolism,antioxidation capacity,and visceral fatty acid profile in finishing Angus bulls

Effect of changing the proportion of C16∶0 and cis-9 C18∶1 in fat supplements on rumen fermentation,glucose and lipid metabolism,antioxidation capacity,and visceral fatty acid profile in finishing Angus bulls

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This study evaluated the effects of different proportions of palmitic(C16∶0)and oleic(cis-9 C18∶1)acids in fat supplements on rumen fermentation,glucose(GLU)and lipid metabolism,antioxidant function,and visceral fat fatty acid(FA)composition in Angus bulls.The design of the experiment was a ran-domized block design with 3 treatments of 10 animals each.A total of 30 finishing Angus bulls(21±0.5 months)with an initial body weight of 626±69 kg were blocked by weight into 10 blocks,with 3 bulls per block.The bulls in each block were randomly assigned to one of three experimental diets:(1)control diet without additional fat(CON),(2)CON+2.5％palmitic calcium salt(PA;90％C16∶0),(3)CON+2.5％mixed FA calcium salts(MA;60％C16∶0+30％cis-9 C18∶1).Both fat supplements increased C18∶0 and cis-9 C18∶1 in visceral fat(P＜0.05)and up-regulated the expression of liver FA transport protein 5(FATP5;P＜0.001).PA increased the insulin concentration(P＜0.001)and aspartate aminotransferase activity(AST;P=0.030)in bull's blood while reducing the GLU concentration(P=0.009).PA increased the content of triglycerides(TG;P=0.014)in the liver,the content of the C16∶0 in visceral fat(P=0.004),and weight gain(P=0.032),and up-regulated the expression of liver diacylglycerol acyltransferase 2(DGAT2;P＜0.001)and stearoyl-CoA desaturase 1(SCD1;P＜0.05).MA increased plasma superoxide dismutase activity(SOD;P=0.011),reduced the concentration of acetate and total volatile FA(VFA)in rumen fluid(P＜0.05),and tended to increase plasma non-esterified FA(NEFA;P=0.069)concentra-tions.Generally,high C16∶0 fat supplementation increased weight gain in Angus bulls and triggered the risk of fatty liver,insulin resistance,and reduced antioxidant function.These adverse effects were alle-viated by partially replacing C16∶0 with cis-9 C18∶1.

Palmitic acidOleic acidLipid metabolismLipotoxicityFinishing bull

Haixin Bai、Lubo Wang、Modinat Tolani Lambo、Yang Li、Yonggen Zhang

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College of Animal Science and Technology,Northeast Agricultural University,Harbin 150030,China

earmarked fund for CARS36Natural Science Foundation of Heilongjiang Province,Chinathe"Academic Backbone"Project of Northeast Agricultural University,China

YQ2023C01122XG35

2024

10.1016/j.aninu.2024.04.010

动物营养(英文)

动物营养(英文)

CSTPCD
ISSN：
年,卷(期)：2024.18(3)