Effects of Particulate Matter on Gut-Lung Axis in Animals and Mitigation Strategies
Particulate matter(PM)in livestock and poultry houses severely damages the respiratory system of animals and workers,and the smaller the particle size,the greater the harm.Particulate matter damages the lung tissue structure,induces lung inflammation and damage,and changes the composition of lung microbiota.In addition,particulate matter can also lead to gut microbiota disorder,increase intestinal permeability,resul-ting in gut microbiota to shift easily or gut derived metabolites affecting the development of lung injury through the gut-lung axis.Reducing the harm of particulate matter in livestock and poultry houses can be achieved through installing filtration systems,ventilation and air ionization,as well as feed processing and adding green additives.This article mainly reviews the impact of particulate matter on the gut-lung axis of animals,and ex-plores the mitigation strategies of particulate matter on animal health such as physical methods,feed processing and nutritional regulation methods,in order to find effective measures to alleviate the impact of particulate mat-ter on animal health.[Chinese Journal of Animal Nutrition,2023,35(12):7530-7540]