首页|细胞焦亡的分子机制及其营养调控

细胞焦亡的分子机制及其营养调控

Molecular Mechanisms of Cell Pyroptosis and Its Nutritional Regulation

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细胞焦亡即炎症坏死,是当前几种常见的细胞死亡方式之一,其与炎症反应密切相关,参与多种疾病的发生,在机体免疫应答过程中发挥重要作用.目前对于细胞焦亡的分子机制研究较为成熟,本篇综述结合近些年国内外在细胞焦亡方面最新的研究进展,阐述了细胞焦亡的经典途径与非经典途径,并介绍了多种营养物质对细胞焦亡途径中关键因子的营养调控作用,以期为细胞焦亡相关病症的防治提供新思路.
Cell pyroptosis,namely inflammatory necrosis,is one of several common modes of cell death,which is closely related to inflammatory response,participates in the occurrence of many diseases,and plays an important role in the process of immune response.Current research on the molecular mechanism of cell pyrop-tosis has a relatively mature system,this review combined with recent years in the latest research progress,ex-pounds the canonical pathway and non-canonical pathway of cell pyroptosis,and introduces the nutritional reg-ulation of a variety of nutrients on the key factors in cell pyroptosis pathway,in order to provide new ideas for the prevention and treatment of cell pyroptosis related disease.[Chinese Journal of Animal Nutrition,2023,35(12):7648-7657]

cell pyroptosiscaspasenutritional regulationcell death

周杨淑、喻礼怀、董丽

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扬州大学动物科学与技术学院,扬州 225009

细胞焦亡 半胱天冬蛋白酶 营养调控 细胞死亡

苏北科技专项富民强村科技帮促项目&&

SZ-HAX202205SJCX23_1992

2023

动物营养学报
中国畜牧兽医学会

动物营养学报

CSTPCDCSCD北大核心
影响因子:1.297
ISSN:1006-267X
年,卷(期):2023.35(12)
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