Effects of Combination of Glucose Oxidase and Catalase on Growth Performance,Nutrient Digestibility,Serum Indices and Intestinal Morphology of Broilers
This experiment was conducted to investigate the effects of combination of glucose oxidase(GOD)and catalase(CAT)on growth performance,nutrient digestibility,serum indices and intestinal morphology of broilers.A total of 600 one-day-old healthy Ross 308 white feather broilers were randomly assigned to 6 groups with 10 replicates in each group and 10 broilers in each replicate(half male and half female).Broilers in the control group were fed a basal diet,and others in experimental groups were fed basal diets supplemented with 250 g/t GOD,250 g/t CAT,250 g/t GOD+125 g/t CAT,250 g/t GOD+250 g/t CAT and 250 g/t GOD+500 g/t CAT,respectively.The experiment was divided into two stages:1 to 21 days of age and 22 to 42 days of age,and the experiment lasted for 42 days.The results showed as follows:1)during 1 to 21 days of age,compared with the control group,the body weight at 21 days of age and average daily gain of 250 g/t GOD+250 g/t CAT group were significantly increased(P＜0.05),and the feed to gain was significantly decreased(P＜0.05).2)Compared with the control group,the ether extract digestibility during 1 to 21 days of age of 250 g/t GOD+250 g/t CAT group was significantly increased(P＜0.05),and the digestibility of dry matter,crude protein and gross energy was increased by 1.94％,1.47％and 2.37％,respectively(P＞0.05).3)Com-pared with the control group,the serum albumin content at 21 days of age of 250 g/t GOD group was signifi-cantly increased(P＜0.05),the serum immunoglobulin G content of 250 g/t CAT group was significantly in-creased(P＜0.05),and the serum immunoglobulin A content of 250 g/t GOD+125 g/t CAT group was sig-nificantly increased(P＜0.05).4)Compared with the control group,the serum superoxide dismutase activity at 21 days of age of 250 g/t CAT group was significantly decreased(P＜0.05),and the serum malondialde-hyde content of 250 g/t GOD+125 g/t CAT group was significantly increased(P＜0.05).5)Compared with the control group,the ileal crypt depth at 21 days of age of 250 g/t GOD+125 g/t CAT group and 250 g/t GOD+250 g/t CAT group was significantly decreased(P＜0.05).In conclusion,dietary addition of 250 g/t GOD+250 g/t CAT can improve growth performance and nutrient digestibility of broilers during 1 to 21 days of age,and addition of 250 g/t GOD+125 g/t CAT and 250 g/t GOD+250 g/t CAT can promote the intesti-nal development of broilers.[Chinese Journal of Animal Nutrition,2023,35(12):7748-7758]
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