首页|红曲菌对黄羽肉鸡生长性能、免疫功能、血浆生化指标、抗氧化能力和脂质代谢的影响

红曲菌对黄羽肉鸡生长性能、免疫功能、血浆生化指标、抗氧化能力和脂质代谢的影响

Effects of Monascus on Growth Performance,Immune Function,Plasma Biochemical Indexes,Antioxidant Capacity and Lipid Metabolism of Yellow-Feathered Chickens

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本试验旨在研究红曲菌对黄羽肉鸡生长性能、免疫功能、血浆生化指标、抗氧化能力和脂质代谢的影响,为其在肉鸡饲养中的应用提供参考.选择288只1日龄且健康状况良好的麻黄肉鸡,随机分为2个组,每组6个重复,每个重复24只(公母各占1/2).对照组饲喂基础饲粮,红曲菌组在基础饲粮中添加500 mg/kg红曲菌.试验期51 d.结果表明,与对照组相比:1)红曲菌组肉鸡22～42日龄和43～51日龄平均日增重显著升高(P＜0.05),22～42日龄、43～51日龄和1～51日龄料重比显著降低(P＜0.05).2)红曲菌组肉鸡21和51日龄脾脏指数均显著升高(P＜0.05).3)红曲菌组肉鸡21 日龄血浆总蛋白(TP)和总胆红素(TBILI)含量均显著升高(P＜0.05),尿酸(UA)含量和谷草转氨酶(AST)活性均显著降低(P＜0.05);红曲菌组肉鸡51日龄血浆TBILI和CRE含量以及乳酸脱氢酶(LDH)活性均显著升高(P＜0.05),UA含量和谷丙转氨酶(ALT)活性均显著降低(P＜0.05).4)红曲菌组肉鸡21日龄空肠黏膜白细胞介素-1β(IL-1β)含量和51日龄空肠黏膜肿瘤坏死因子-α(TNF-α)含量均显著降低(P＜0.05),21和51日龄空肠黏膜白细胞介素-10(IL-10)含量显著升高(P＜0.05).5)红曲菌组肉鸡肝脏总超氧化物歧化酶(T-SOD)和谷胱甘肽过氧化物酶(GSH-Px)活性均显著升高(P＜0.05),肾脏丙二醛(MDA)含量显著降低(P＜0.05),肾脏GSH-Px活性显著升高(P＜0.05).6)红曲菌组肉鸡21和51日龄血浆以及21日龄肝脏高密度脂蛋白胆固醇(HDL-C)含量显著降低(P＜0.05),21日龄血浆低密度脂蛋白胆固醇(LDL-C)含量显著降低(P＜0.05).综上所述,饲粮中添加500 mg/kg红曲菌可提高1～51日龄黄羽肉鸡生长性能、免疫功能和抗氧化能力,同时调节脂质代谢.
This experiment was conducted to investigate the effects of Monascus on growth performance,im-mune function,plasma biochemical indexes,antioxidant capacity and lipid metabolism of yellow-feathered chickens,to provide reference for its application in chicken feeding.A total of 288 one-day-old healthy ephedra chickens were randomly divided into 2 groups with 6 replicates in each group and 24 chickens in each replicate(half male and half female).Chickens in the control group were fed a basal diet,and chickens in the Monas-cus group were fed the basal diet supplemented with 500 mg/kg Monascus.The experiment lasted for 51 days.The results showed that compared with the control group:1)The average daily gain of chickens during 22 to 42 days of age and 43 to 51 days of age of Monascus group was significantly increased(P＜0.05),and the ra-tio of feed to gain of chickens during 22 to 42 days of age,43 to 51 days of age and 1 to 51 days of age of Monascus group was significantly decreased(P＜0.05).2)The spleen index of chickens at 21 and 51 days of age of Monascus group was significantly increased(P＜0.05).3)The contents of total protein(TP)and total bilirubin(TBILI)in plasma of chickens at 21 days of age of Monascus group were significantly increased(P＜0.05),and the uric acid(UA)content and aspartate aminotransferase(AST)activity were significantly de-creased(P＜0.05);the TP and TBILI contents and lactate dehydrogenase(LDH)activity in plasma of chick-ens at 51 days of age of Monascus group were significantly increased(P＜0.05),and the UA content and ala-nine aminotransferase(ALT)activity were significantly decreased(P＜0.05).4)The content of interleukin-10(IL-10)in jejunal mucosa of chickens at 21 days of age and content of tumor necrosis factor-α(TNF-α)in jejunal mucosa of chickens at 51 days of age of Monascus group were significantly decreased(P＜0.05),and the content of interleukin-10(IL-10)in jejunal mucosa of chickens at 21 and 51 days of age was signifi-cantly increased(P＜0.05).5)The activities of total superoxide dismutase(T-SOD)and glutathione peroxi-dase(GSH-Px)in liver of chickens of Monascus group were significantly increased(P＜0.05),the kidney malondialdehyde(MDA)content was significantly decreased(P＜0.05),and the kidney GSH-Px activity was significantly increased(P＜0.05).6)The content of high density lipoprotein cholesterol(HDL-C)in plasma of chickens at 21 and 51 days of age and in liver of chickens at 21 days of age of Monascus group was signifi-cantly decreased(P＜0.05),and the content low density lipoprotein cholesterol(LDL-C)content in plasma of chickens at 21 days of age was significantly decreased(P＜0.05).In summary,dietary 500 mg/kg Monascus can improve the growth performance,immune function and antioxidant capacity of yellow-feathered chickens during 1 to 51 days of age,and regulate the lipid metabolism.[Chinese Journal of Animal Nutrition,2023,35(12):7774-7785]

Monascusyellow-feathered chickensgrowth performanceimmune functionantioxidant capac-itylipid metabolism

苏青云、熊太第、张盛、叶金玲、罗琦丽、苟钟勇、蒋守群、范秋丽

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广东省农业科学院动物科学研究所,猪禽种业全国重点实验室,农业农村部华南动物营养与饲料重点实验室,广东省畜禽育种与营养研究重点实验室,广州 510640

广东南宝集团茂名市金盈饲料有限公司,茂名 525024

红曲菌 黄羽肉鸡 生长性能 免疫功能 抗氧化能力 脂质代谢

国家重点研发计划项目广东省重点领域研发计划项目现代农业产业技术体系国家肉鸡产业技术体系项目广东省自然科学基金广东省自然科学基金广东省自然科学基金广州市科技计划项目广东省农业科学院科技计划项目广东省农业科学院科技计划项目广东省畜禽育种与营养研究重点实验室开放课题

2021YFD13004042020B0202090004CARS-412021A15150124122021A15150108302022A1515012069202206010168202106TDR2019PY-QF0082021SZ03

2023

10.12418/CJAN2023.706

动物营养学报
中国畜牧兽医学会

动物营养学报

CSTPCDCSCD北大核心
影响因子：1.297
ISSN：1006-267X
年,卷(期)：2023.35(12)
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