Regulatory Effects of Attapulgite on Animal Intestinal Barrier Functions and Its Application in Livestock and Poultry Production
Attapulgite is a layer chain crystalline hydrated magnesium-aluminosilicate mineral,also known as palygorskite,which can adsorb bacteria,heavy metals,mycotoxins,and bacterial toxins effectively and repair and protect the gastrointestinal mucosa of animals.It is reported that dietary supplementation with attapulgite can improve gut morphology,increase the number of goblet cells in the intestine,promote the expression of tight junction proteins in the intestinal tract,regulate intestinal microbiota balance,increase the levels of immu-noglobulins in the intestine,inhibit the gene expressions of pro-inflammatory factors,and improve animal per-formance.In addition,attapulgite has demonstrated the ability to effectively mitigate the impairment of animal intestinal barrier functions caused by mycotoxins,pathogenic bacteria,lipopolysaccharide,and other patho-gens.This paper reviewed the research progress on the effects of attapulgite on animal intestinal barrier func-tions and summarized the latest research findings on the application of attapulgite in animal production,in order to provide theoretical references for improving animal intestinal health through nutritional regulation and at-tapulgite using in animal production.[Chinese Journal of Animal Nutrition,2024,36(1):25-32]