Research Progress on Harm of Ochratoxin A to Animals and Its Detoxification
Ochratoxin A(OTA)is a secondary metabolite produced by Aspergillus or penicillium,which widely contaminates agricultural products and feeds such as grains,fruits and nuts,causing serious economic losses.In addition,there is growing evidence that OTA poses a significant threat to human and animal health through multiple toxic effects(nephrotoxicity,hepatotoxicity,enterotoxicity,carcinogenicity,teratogenicity and immunotoxicity).Therefore,it is urgent to study the toxicity mechanism of OTA and seek detoxification methods from various aspects.In this paper,the harm of OTA to animals and its detoxification methods were reviewed,with emphasis on the advantages and disadvantages of various OTA detoxification methods,and the methods to improve the efficiency of OTA detoxification were discussed in depth,in order to reduce the content of OTA in feed and help reduce the harm caused by OTA to animal health.[Chinese Journal of Animal Nutri-tion,2024,36(1):107-114]
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