摘要
伏马菌素B1(FB1)是由镰刀菌产生的水溶性代谢产物,存在于镰刀菌污染了的谷物、油料作物、坚果、饲草和饲料中,是常见的真菌毒素之一.FB1会对神经系统、呼吸系统、消化系统和生殖系统产生不同毒性作用,给农牧业造成不可估量的经济损失.如何对FB1进行脱毒,以降低其毒性作用,是目前研究的热点.因此,本文对FB1的物理脱毒、化学脱毒、生物脱毒及其应用进行综述,重点对常用于FB1生物脱毒的菌株和酶及其脱毒效果、脱毒机制进行了深入探讨,以期为提高FB1脱毒效率和开发新的FB1脱毒方法提供参考和思路.
Abstract
Fumonisin B1(FB1)is a water-soluble metabolite produced by Fusarium oxysporum,which is one of the prevalent mycotoxins,naturally occurring in cereals,oilseed crops,nuts,forage and feedstuffs.FB1 ex-posure can produce different toxic effects on the nervous system,respiratory system,digestive system and re-productive system,causing immeasurable economic losses in global agriculture and animal husbandry.The cur-rent research focus lies in the detoxification of FB1 and mitigation of its toxic impact.Therefore,this article comprehensively reviewed the physical,chemical,biological methods and applications of FB1 detoxification.With a particular focus on the strains and enzymes commonly used for FB1 biodetoxification,as well as their detoxification effects and mechanisms,a thorough and detailed discussion was pursued,aiming to provide ref-erence and ideas for improving the detoxification efficiency of FB1 and developing a new FB)detoxification method.[Chinese Journal of Animal Nutrition,2024,36(1):115-123]
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