Effects of Quercetagetin on Growth Performance,Antioxidant Capacity,Immune Function and Cecal Microflora of Weaned Piglets
The aim of this experiment was to investigate the effects of dietary supplemented with quercetagetin on growth performance,antioxidant capacity,immune function and cecal microflora of weaned piglets.One hundred and forty-four weaned piglets at 28 days of age and with the average body weight of(10.40±1.97)kg were selected and divided into four groups with six replicates per group and six pigs(half male and half fe-male)per replicate.The diets of the four groups were supplemented with 0(control group),150(test groupⅠ),300(test group Ⅱ)and 450 mg/kg(test group Ⅲ)of quercetagetin based on a basal diet,respectively.Piglets were fed for 31 days,with a pre-test period of 3 days and a trial period of 28 days.The average daily gain,average daily feed intake,feed to gain ratio and diarrhea rate were calculated at the end of the trial;four piglets of each group were slaughtered and sampled for the determination of duodenal antioxidant enzyme activ-ities and secreted immunoglobulin(sIgA)content,serum immunoglobulin and cytokine contents,and the composition of cecal microflora.The results showed that dietary supplemented with different levels of quercet-agetin had no significant effects on the growth performance of weaned piglets compared with control group(P＜0.05),but the supplementation of quercetagetin at 300 mg/kg could significantly reduce the diarrhea rate(P＜0.05),significantly increase the duodenal catalase,superoxide dismutase activities and sIg A content(P＜0.05),significantly reduce the serum interleukin-2(IL-2)and tumor necrosis factor-a(TNF-ce)contents(P＜0.05),and tend to decrease the relative abundance of Proteobacteria in cecal flora(P=0.094).It can be seen that the supplementation of quercetagetin at 300 mg/kg can improve the antioxidant capacity and immune function of weaned piglets,reduce the proportion of harmful bacteria in cecum,and then reduce the diarrhea rate and maintain intestinal health.[Chinese Journal of Animal Nutrition,2024,36(1):199-209]
万方数据
维普
