The aim of this experiment was to investigate the effects of dietary supplemented with quercetagetin on growth performance,antioxidant capacity,immune function and cecal microflora of weaned piglets.One hundred and forty-four weaned piglets at 28 days of age and with the average body weight of(10.40±1.97)kg were selected and divided into four groups with six replicates per group and six pigs(half male and half fe-male)per replicate.The diets of the four groups were supplemented with 0(control group),150(test groupⅠ),300(test group Ⅱ)and 450 mg/kg(test group Ⅲ)of quercetagetin based on a basal diet,respectively.Piglets were fed for 31 days,with a pre-test period of 3 days and a trial period of 28 days.The average daily gain,average daily feed intake,feed to gain ratio and diarrhea rate were calculated at the end of the trial;four piglets of each group were slaughtered and sampled for the determination of duodenal antioxidant enzyme activ-ities and secreted immunoglobulin(sIgA)content,serum immunoglobulin and cytokine contents,and the composition of cecal microflora.The results showed that dietary supplemented with different levels of quercet-agetin had no significant effects on the growth performance of weaned piglets compared with control group(P＜0.05),but the supplementation of quercetagetin at 300 mg/kg could significantly reduce the diarrhea rate(P＜0.05),significantly increase the duodenal catalase,superoxide dismutase activities and sIg A content(P＜0.05),significantly reduce the serum interleukin-2(IL-2)and tumor necrosis factor-a(TNF-ce)contents(P＜0.05),and tend to decrease the relative abundance of Proteobacteria in cecal flora(P=0.094).It can be seen that the supplementation of quercetagetin at 300 mg/kg can improve the antioxidant capacity and immune function of weaned piglets,reduce the proportion of harmful bacteria in cecum,and then reduce the diarrhea rate and maintain intestinal health.[Chinese Journal of Animal Nutrition,2024,36(1):199-209]
维普
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