Effects of Lactobacillus and Isomalto-Oligosaccharide Compound Supplementation on Growth Performance,Nutrient Apparent Digestibility,Immune Function and Antioxidant Capacity of Sucking Calves
This study was conducted to investigate the effects of dietary synbiotics composed of Limosilactoba-cillus reuteri,Lactobacillus johnsonii and isomalto-oligosaccharide on growth performance,nutrient apparent digestibility,immune function and antioxidant capacity of sucking calves.Forty healthy(10±2)-day-old Chi-nese Holstein cow calves with similar body weight were randomly divided into 4 groups with 10 calves per group.Calves in the control group(HSY0 group)were fed a basal diet,and those in the experimental groups were fed the basal diet supplemented with 2.5(HSY2.5 group),5.0(HSY5.0 group)and 10.0 g/(d·head)(HSY10.0 group)synbiotic preparations,respectively.The experiment lasted for 42 days.The results showed as follows:1)compared with the control group(HSY0 group),the body weight of calves on day 21 in HSY5.0 group was significantly increased(P＜0.05);the body weight on day 42 in the three experimental groups was significantly increased(P＜0.05),and which in HSY5.0 group was significantly higher than that in HSY2.5 and HSY10.0 groups(P＜0.05).Compared with the control group,the average daily gain(ADG)of calves at all stages in HSY5.0 group was significantly increased(P＜0.05);from days 1 to 42,ADG in the three experimental groups was significantly increased(P＜0.05),and which in HSY5.0 group was significantly higher than that in HSY2.5 and HSY10.0 groups(P＜0.05).2)Compared with the control group,on day 21,the body height,heart girth and chest depth of calves in HSY5.0 group were significantly increased(P＜0.05);on day 42,the body height,heart girth and chest depth in three experimental groups were significantly increased(P＜0.05),and the body dip length,heart girth and chest depth in HSY5.0 group were significantly higher than those in HSY2.5 and HSY10.0 groups(P＜0.05),while the body height was significantly higher than that in HSY2.5 group(P＜0.05).3)Compared with the control group,the apparent digestibility of dry matter(DM),crude protein(CP)and neutral detergent fiber(NDF)of calves in HSY5.0 group was signifi-cantly increased(P＜0.05).4)Compared with the control group,on day 21,the serum contents of triglycer-ide(TG)and urea nitrogen(UN)of calves in HSY5.0 group were significantly decreased(P＜0.05);on day 42,the serum TG content in the three experimental groups was significantly decreased(P＜0.05),and which in HSY5.0 group was significantly lower than that in HSY2.5 and HSY10.0 groups(P＜0.05);the serum UN content in HSY5.0 group was significantly decreased(P＜0.05).5)Compared with the control group,from days 1 to 21,the fecal score of calves in HSY5.0 group was significantly decreased(P＜0.05),and the diar-rhea rate in the three experimental groups was significantly decreased(P＜0.05);from days 22 to 42,the fecal score and diarrhea rate in the three experimental groups were significantly decreased(P＜0.05);from days 1 to day 42,the fecal score and diarrhea rate in HSY5.0 and HSY10.0 groups were significantly decreased(P＜0.05).6)Compared with the control group,on day 21,the serum contents of immunoglobulin G(IgG)and tumor necrosis factor-α(TNF-α)as well as total antioxidant capacity(T-AOC)of calves in HSY5.0 group were significantly increased(P＜0.05),and the serum contents of malondialdehyde(MDA)and interleukin-1β(IL-1β)were significantly decreased(P＜0.05);on day 42,the serum contents of immunoglobulin A(IgA),immunoglobulin M(IgM),IgG and TNF-α as well as T-AOC in HSY5.0 group were significantly increased(P＜0.05),and the serum MDA content in the three experimental groups was significantly decreased(P＜0.05),while there was no significant difference among the three groups(P＞0.05).In conclusion,dieta-ry synbiotics can improve the growth performance,body size indices and apparent digestibility of nutrients,en-hance the immune function and antioxidant capacity,and reduce the diarrhea rate of suckling calves,and the effect of 5.0 g/(d·head)is the best.[Chinese Journal of Animal Nutrition,2024,36(1):360-373]
万方数据
维普
