This experiment was conducted to investigate the effects of dietary garlic peel on growth perform-ance,rumen fermentation parameters,serum biochemical,immune and antioxidant indices of Hu sheep.Thir-ty-two healthy male lambs of Hu sheep about 3.5 months of age with similar body weight[(23.85±0.41)kg]were randomly divided into 2 groups with 16 lambs in each group.The control group(CON group)was fed a basal diet,and the garlic peel group(GAP group)was fed the basal diet used 3%garlic peel instead of all wheat straw.The experiment lasted for 28 days.The results showed as follows:1)compared with CON group,dietary garlic peel significantly increased the average growth rates of body weight and chest circumfer-ence(P<0.01).2)Compared with CON group,dietary garlic peel dietary garlic peel significantly increased the rumen butyric acid(BA)ratio(P<0.05),significantly decreased the rumen isobutyric acid(IBA)ratio(P<0.05),and significantly decreased the rumen isovaleric acid(IVA)ratio(P<0.01).3)Compared with CON group,dietary garlic peel dietary garlic peel significantly decreased the serum total cholesterol(TC)con-tent(P<0.01),significantly decreased the serum triglyceride(TG)content(P<0.05),and significantly in-creased the serum total protein(TP)content(P<0.01).4)Compared with CON group,dietary garlic peel dietary garlic peel significantly increased the contents of immunoglobulin A(IgA)and immunoglobulin M(IgM)in serum(P<0.05),and significantly increased the serum immunoglobulin G(IgG)content(P<0.01).5)Compared with CON group,dietary garlic peel dietary garlic peel significantly decreased the serum malondialdehyde(MDA)content(P<0.01),and significantly increased the total antioxidant capacity(T-AOC)and activities of total superoxide dismutase(T-SOD),glutathione-peroxidase(GSH-Px),catalase(CAT)in serum(P<0.01).In conclusion,dietary addition of 3% garlic peel can improve serum biochemical indexes,enhance immunity and antioxidant capacity,increase rumen butyric acid ratio,and then improve the growth performance of Hu sheep.[Chinese Journal of Animal Nutrition,2024.36(1):406-415]