Intestinal mucin is a type of macromolecular glycoprotein composed of mucopolysaccharides,which is synthesized and secreted by goblet cells.The main function of the intestinal mucin is to maintain the integrity and functionality of the intestinal mucosal barrier by binding to the adhesion molecules on the surface of intesti-nal mucosal epithelial cells.The research of gut related mucin and gut mucosal barrier is crucial for regulating animal intestinal health.This review provides an overview of the structure,types and physiological functions of the mucin,as well as their relationship with the intestinal mucosal barrier.In addition,this review also intro-duces the close relationship between intestinal mucin and intestinal inflammation as well as other intestinal dis-eases.This review will play an important theoretical foundation for in-depth exploration of the role and related mechanisms of mucin in animal intestines,and provide important reference for the prevention and treatment strategies of human intestinal diseases.[Chinese Journal of Animal Nutrition,2024,36(3):1484-1493]
万方数据
维普
