首页|动物肌内脂肪沉积的影响因素及其分子机制

动物肌内脂肪沉积的影响因素及其分子机制

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肌内脂肪(IMF)指在肌肉内、肌纤维间所沉积的脂肪,其含量与肌肉的多汁度、剪切力、嫩度以及肉质显著正相关,因此合理的IMF含量将有助于改善肉品的质量和提高其风味.IMF生成的过程涉及复杂且高度协调的基因表达调控程序,受多种因素影响.因此,本文综述了影响动物IMF沉积的转录因子、关键代谢酶、信号通路以及非编码RNA.研究显示,转录因子在调节脂肪细胞分化和脂肪合成的过程中起着重要作用;酶催化反应则介导了脂肪生成和降解的关键步骤;此外,通过调控特定信号通路和非编码RNA的表达,也能够对IMF沉积进行调控.深入了解和运用这些分子机制对于肉制品质量的提升和生产优质肉制品具有重要意义.本综述为进一步研究和运用这些分子机制提供了参考依据,以期改善肉制品的质量,满足消费者对优质肉制品的需求.
Affecting Factors of Intramuscular Fat Deposition in Animals and Their Molecular Mechanisms
Intramuscular fat(IMF)refers to the fat deposited in the muscle and between muscle fibers.Its con-tent is significantly positively correlated with muscle juiciness,shear force,tenderness and meat quality.There-fore,reasonable IMF content will help improve the quality and flavor of meat products.The process of adipo-genesis involves a complex and highly coordinated gene expression regulation program,which is affected by many factors.Therefore,this paper reviews the transcription factors,key metabolic enzymes,signaling path-ways and non-coding RNAs that affect animal IMF deposition.Studies indicates that transcription factors have been found to play an important role in regulating adipocyte differentiation and fat synthesis,enzyme-catalyzed reactions mediate the key steps of lipogenesis and degradation;in addition,intramuscular fat deposition can al-so be regulated by regulating the expression of specific signaling pathways and non-coding RNAs.In-depth un-derstanding of these molecular mechanisms is of great significance for the improvement of meat quality and the production of high-quality meat products.This review provides a reference for further research and application of these molecular mechanisms,in order to improve the quality of meat products and meet consumers'demand for high-quality meat products.[Chinese Journal of Animal Nutrition,2024,36(3):1502-1514]

intramuscular fatmeat qualitytranscription factorssignaling pathwaysenzymesnon-coding RNAs

李银、韦洋洋、蒋钦杨、黄艳娜

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广西大学动物科学技术学院,南宁 530004

肌内脂肪 肉品质 转录因子 信号通路 非编码RNA

广西自然科学基金国家自然科学基金

2022GXNSFAA03552531760672

2024

动物营养学报
中国畜牧兽医学会

动物营养学报

CSTPCD北大核心
影响因子:1.297
ISSN:1006-267X
年,卷(期):2024.36(3)
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