Effects of Compound Bacteria Culture on Performance,Non-Specific Immune Function and Antioxidant Capacity of Dairy Cows
This experiment was conducted to study the effects of compound bacteria culture on performance,non-specific immune function and antioxidant capacity of dairy cows.Forty healthy Holstein cows with two par-ities and similar lactation days[(92.1±25.6)d],milk yield[(36.8±4.6)kg/d]and milk protein content[(2.98±0.48)%]were randomly divided into 2 groups with 20 cows per group.Cows in the control group were fed a basal diet,and those in the experimental group were fed the basal diet supplemented with 0.23 kg/d compound bacteria culture.The pre-trial period lasted for 7 days and the experimental period lasted for 60 days.Feed intake and milk yield were recorded daily during the experiment.Milk was collected every 20 days to de-termine the milk composition,and blood was collected at the beginning and ending of the experiment to deter-mine the immune and antioxidant indices.The results showed as follows:1)on days 41 to 60 of the experi-ment,the average daily feed intake of cows in the control group was decreased by 2.92%compared with days 1 to 20 of the experiment,while it was increased by 3.12%in the experimental group.On days 21 to 40 and 41 to 60,the milk yield of cows in the experimental group was increased by 2.17(P<0.01)and 2.42 kg/d(P<0.05)compared with that in the control group,respectively.During the experiment,there were no signifi-cant differences in milk protein and non-fat milk solid contents between 2 groups(P>0.05).2)On day 60,the serum lysozyme(LZM)content,acid phosphatase(ACP)activity,lymphocyte proliferation capacity and neutrophil phagocytosis capacity of cows in the experimental group were significantly higher than those in the control group(P<0.05),the total antioxidant capacity(T-AOC),activities of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in serum in the experimental group were significantly increased by 11.54%,22.09%and 17.18%compared with the control group(P<0.05),and the serum malondialdehyde content was significantly decreased by 35.38%compared with the control group(P<0.05),respectively.The results indicate that the compound bacterial culture can significantly increase feed intake and milk yield,im-prove non-specific immune function and enhance antioxidant capacity of dairy cows.[Chinese Journal of Ani-mal Nutrition,2024,36(4):2416-2424]