Application of Metabolomics Technology in Screening Biomarkers of Mastitis in Dairy Cows
With the continuous expansion of the scale of dairy cow breeding,the incidence of common diseases in dairy cows is also increasing year by year.The screening of the markers to accurately determine the disease onset of dairy cows can be an early warning of the onset of dairy cows.The application of metabolomics tech-niques based on nuclear magnetic resonance spectroscopy,gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry has been widely used in dairy diseases and dairy products,but lacks under-standing of the correlation between changes in breast inflammatory markers and metabolite levels and clinical signs.This review summarizes relevant studies on screening biomarkers of mastitis in dairy cows using metabo-lomics techniques,to provide technical support for rapid and accurate diagnosis of cow mastitis in production practice.[Chinese Journal of Animal Nutrition,2024,36(6):3474-3481]