Research Progress on Effects of Selenium,Iron,Zinc and Copper on Animal Health and Their Epigenetic Regulatory Mechanisms
Trace mineral elements(referred to as trace elements)exist in a small amount in the animal body,but they are vital to the physiological function of the body.Research has proved that trace elements through epi-genetic regulation on the animal body impact,play a role in improving animal productivity,prevention and control of animal diseases,can reduce feeding costs,improve the quality of animal products(meat,eggs and milk,etc.).Epigenetics is defined as the phenomenon and mechanism of heritable gene expression changes that lead to chromosomal changes independent of DNA sequence changes.It has been a hot research topic in recent years,and its regulatory mechanisms include DNA methylation,histone modification and regulation of non-coding RNA,etc.This paper mainly discusses the effects of common trace elements such as selenium,iron,zinc and copper on animal health and their epigenetic regulation and mechanism,in order to provide some ref-erence for future research and application.[Chinese Journal of Animal Nutrition,2024,36(6):3563-3572]
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