The aim of this experiment was to investigate the effects of Clostridium butyricum on growth per-formance,serum antioxidant indexes and diarrhea frequency of lactating calves.Seventy-five healthy 1-day-old Holstein female calves with similar body weight[(40±3)kg]were randomly divided into 5 groups with 15 calves per group.The control group(CB0 group)was fed a basal diet,while the experimental groups were fed the basal diets supplemented with 0.2(CB0.2 group),0.4(CB0.4 group),0.8(CB0.8 group)and 1.6 g/d(CB1.6 group)Clostridium butyricum,respectively.The experiment lasted for 60 days.The results showed as follows:1)there was no significant difference in growth performance among all groups(P>0.05).2)At 14 and 42 days of age,the serum superoxide dismutase(SOD)activity of CB0.8 group was significantly higher than that of CB0 group(P<0.01),and significantly higher than that of CB0.4 group(P<0.05).At 28 days of age,the serum malondialdehyde(MDA)content of CB0.8 group was significantly lower than that of CB0 group(P<0.01),and the serum MDA content of CB0.2,CB0.4 and CB1.6 groups was significantly lower than that of CB0 group(P<0.05).3)During 29 to 42 days of age,43 to 60 days of age and 3 to 60 days of age,the diarrhea frequency of CB0.2,CB0.4,CB0.8 and CB1.6 groups was significantly lower than that of CB0 group(P<0.05 or P<0.01).In conclusion,the Clostridium butyricum has no effect on the growth per-formance of lactating calves,but can increase the serum SOD activity of lactating calves at 14 and 42 days of age,and decrease the serum MDA content at 28 days of age,decrease the diarrhea frequency.Under the con-dition of this experiment,the 0.8 g/d Clostridium butyricum has the best effect for reducing the diarrhea fre-quency of lactating calves.[Chinese Journal of Animal Nutrition,2024,36(6):3772-3780]
关键词
哺乳犊牛/丁酸梭菌/生长性能/抗氧化/腹泻频率
Key words
lactating calves/Clostridium butyricum/growth performance/antioxidant/diarrhea frequency