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鸡感染性输卵管炎的致病机理及营养干预

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输卵管炎是一种产蛋鸡高发性生殖道疾病,以大肠杆菌为主要病原体的外界致病微生物入侵引发的感染性输卵管炎是其最常见的病变形式,感染性输卵管炎导致蛋鸡产蛋减少甚至停滞.全价的营养物质供给是机体免疫功能正常运行的物质基础,对免疫细胞的成熟、分化和分泌过程发挥关键的调控作用.在炎性病理条件下,额外补充营养物质有助于输卵管免疫功能的恢复,通过调节激素和炎性因子水平,减少淋巴细胞浸润和抑制细胞凋亡,进而缓解输卵管炎症.本文主要阐释了鸡感染性输卵管炎的发病特征及分子机制,并就营养干预措施在降低输卵管炎性反应、维持机体健康中的作用进行系统综述,以期为鸡感染性输卵管炎的科学防治提供理论依据和有效干预措施.
Pathogenesis and Nutritional Regulation of Infectious Salpingitis in Chickens
Salpingitis is a high incidence of reproductive tract diseases in laying hens.The most common form of salpingitis is the invasion of external pathogenic microorganisms with the main pathogen of Escherichia coli,which leads to the egg reduction or even stagnation of laying hens.The supply of full nutrients is the material basis for the normal operation of immune function,and plays a key role in the regulation of the maturation,differentiation and secretion of immune cells.Under inflammatory pathological conditions,additional nutrients can help to restore the immune function of the fallopian tube,reduce lymphocyte infiltration and inhibit apopto-sis by regulating hormone and inflammatory factor levels,and then alleviates salpingitis.In this paper,the pathogenesis and molecular mechanism of infectious salpingitis in chickens were explained,and the effects of nutritional regulation on reducing salpingitis and maintaining body health were systematically reviewed,in order to provide theoretical basis and effective intervention measures for scientific prevention and treatment of infec-tious salpingitis in chickens.[Chinese Journal of Animal Nutrition,2024,36(7):4136-4144]

laying henssalpingitisnutritional regulation

刘泽瑊、吴斯巧、卢盼盼、高春起

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华南农业大学动物科学学院,广东省动物营养调控重点实验室,猪禽种业全国重点实验室,广州 510642

蛋鸡 输卵管炎 营养干预

国家自然科学基金面上项目

31972585

2024

动物营养学报
中国畜牧兽医学会

动物营养学报

CSTPCD北大核心
影响因子:1.297
ISSN:1006-267X
年,卷(期):2024.36(7)