Research Progress on Regulatory Effects and Mechanism of Polyunsaturated Fatty Acids on Mammalian Endometrial Receptivity
Endometrial receptivity is a key factor affecting successful pregnancy in mammals.Endometrial re-ceptivity is regulated by various bioactive factors,and exploring its regulatory role and mechanism is great sig-nificance to improve the reproductive efficiency of female animals.Polyunsaturated fatty acids,as important bioactive molecules that regulate body lipid metabolism,play an important role in the early stages of mammali-an pregnancy,such as regulating endometrial receptivity and decidualization,etc.This article reviews the effects of polyunsaturated fatty acids on endometrial receptivity from various aspects such as regulating prosta-glandin and steroid hormone synthesis and endometrial inflammatory response,with a view to exploring the effects of polyunsaturated fatty acids on endometrial receptivity in mammals,provide reference for the regulato-ry mechanism and its application in animal production.[Chinese Journal of Animal Nutrition,2024,36(7):4222-4232]