动物营养学报2024,Vol.36Issue(8) :4795-4808.DOI:10.12418/CJAN2024.411

益生菌抑制断奶仔猪腹泻的作用及机制

Inhibition Effects and Mechanism of Probiotics on Post-Weaning Diarrhea in Piglets

贾冬文 夏子涵 王家莹 曹阳
动物营养学报2024,Vol.36Issue(8) :4795-4808.DOI:10.12418/CJAN2024.411

益生菌抑制断奶仔猪腹泻的作用及机制

Inhibition Effects and Mechanism of Probiotics on Post-Weaning Diarrhea in Piglets

贾冬文 1夏子涵 1王家莹 1曹阳2
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作者信息

  • 1. 黑龙江八一农垦大学动物科技学院,大庆 163319
  • 2. 黑龙江八一农垦大学动物科技学院,大庆 163319;粮食副产物加工与利用教育部工程研究中心,大庆 163319;黑龙江省寒区饲料资源高效利用与营养调控重点实验室,大庆 163319;大庆市生物饲料开发与安全利用工程技术研究中心,大庆 163319
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摘要

断奶仔猪腹泻是养猪行业的常见疾病,其较高的发病率与死亡率对养猪行业造成较大经济损失.益生菌是一类对动物生命活动有益的微生物,其作为饲料添加剂可起到预防仔猪腹泻,减轻腹泻症状等效果.本文综述了益生菌通过自身增殖并抑制有害微生物保持肠道稳态、产生活性物质巩固肠道屏障、直接或间接与细胞表面受体作用加强肠道免疫能力等方式缓解仔猪腹泻,分析了益生菌对肠道细胞抗炎、抗凋亡的具体作用机制,为充分了解益生菌抑制仔猪腹泻的作用机制及其在仔猪饲养中的应用提供参考.

Abstract

Post-weaning diarrhea is a common disease,and its high morbidity and mortality will cause great e-conomic losses in pig industry.Probiotics are a kind of microorganism beneficial to animal life activities.As feed additives,probiotics can prevent diarrhea and alleviate the diarrhea symptoms of piglets.This paper re-viewed the effects of probiotics on relieving diarrhea in piglets by self-proliferation and inhibiting harmful mi-croorganisms to maintain intestinal homeostasis,producing active substances to consolidate intestinal barrier,and directly or indirectly interacting with cell surface receptors to enhance intestinal immunity,analyzed the specific mechanisms of probiotics on anti-inflammatory and anti-apoptosis of intestinal cells,aiming to provide a reference for fully understanding the mechanism of probiotics inhibiting diarrhea in piglets and its application in piglet feeding.[Chinese Journal of Animal Nutrition,2024,36(8):4795-4808]

关键词

仔猪/腹泻/益生菌/抑制作用/肠道菌群

Key words

piglets/diarrhea/probiotics/inhibition effects/gut microbiota

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出版年

2024
动物营养学报
中国畜牧兽医学会

动物营养学报

CSTPCD北大核心
影响因子:1.297
ISSN:1006-267X
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