Evaluation of Tolerance of Potassium Diformate in Broiler Chickens
This study was aimed to evaluate the tolerance of broiler chickens to the application of potassium di-formate,in accordance with the Guidelines for Evaluating the Tolerance of Animal Target Animals with Feed Raw Materials and Feed Additives(Trial).A total of 360 one-day-old Arbor Acres broilers were randomly di-vided into three groups,with six replicates per groups,and 20 chickens per replicates,half cock and half hens were reared in separate cages.The control group was fed a basal diet,and the treatment groups were supple-mented with 4 and 40 g/kg of potassium diformate based on the basal diet,respectively.The experiment period was 42 days.Results showed as follows:1)compared with 4 g/kg potassium diformate group,40 g/kg potas-sium diformate significantly decreased average daily gain(P<0.05)and significantly increased the ratio of feed to gain of broilers(P<0.05);the average daily feed intake of cocks in 40 g/kg potassium dicarboxylate group was significantly lower than that in 4 g/kg potassium dicarboxylate group(P<0.05).2)Compared with the control group,dietary supplementation of 40 g/kg potassium dicarboxylate significantly increased the number of red blood cells in blood of 21-day-old cocks(P<0.05),and decreased the proportion of intermediate cells in blood of hens(P<0.05).At 42 days of age,compared with the control group,dietary supplementation with 40 g/kg potassium dicarboxylate significantly decreased the plateletcrit of cocks(P<0.05);supplementation with 4 and 40 g/kg potassium dicarboxylate significantly decreased platelet count and plateletcrit in hens(P<0.05).3)Compared with the control group,the inclusion of 40 g/kg potassium diformate in the diet were led to a significant increase the serum urea content(P<0.05),and decreased in uric acid content in 21-day-old cocks(P<0.05).4)Compared with the control group,the addition of potassium diformate to the diet did not have a significant effect on the organ indexes of broiler chickens(P>0.05),and no pathological changes were observed in the tissues.In conclusion,the addition of 40 g/kg potassium diformate to the diet enhances the body's protein metabolism without impacting organ development.However,it observes that this supplementa-tion significantly decreases the growth performance of broiler chickens.These findings confirm that the toler-ance level of broiler chickens to potassium diformate is below 40 g/kg.[Chinese Journal of Animal Nutrition,2024,36(8):4997-5012]