Meta Analysis of Effects of Adding Bacillus subtilis to Diet on Growth Performance of Broilers
Using Meta-analysis to study the effects of adding Bacillus subtilis to the diet on the growth perform-ance of broilers,in order to provide theoretical and data reference for broiler production.Retrieve 34 articles and 21 292 research subjects from domestic and foreign databases that meet the analysis requirements from 2000 to 2023.This study used Stata software for Meta-analysis,conducted heterogeneity tests on the growth performance data of the included articles based on statistical statistic(I2),and analyzed publication bias of the included articles through Egger test.The publication bias of the included articles was analyzed through funnel plots and Egger tests.Due to significant heterogeneity in all indicators analyzed in this study,a random effects model was used to analyze the continuous data,and subgroup analysis was conducted based on the Bacillus species to explore the effects of different Bacillus on the growth performance of broilers.Results showed as fol-lows adding Bacillus subtilis to the diet can significantly increase average daily gain(ADG)of broilers from 1 to 21 days of age[standardized mean difference(SMD)=2.118,95％confidence interval(CI):(1.730,2.506)],and reduce feed/gain(F/G)of broilers[SMD=-1.129,95％CI:(1.440,-0.818)];adding Bacillus subtilis to the diet can significantly increase ADG[SMD=0.657,95％CI:(0.356,0.958)]and av-erage daily feed intake(ADFI)[SMD=0.768,95％CI:(0.483,1.054)]in broilers from 22 to 42 days of age,and reduce F/G[SMD=-1.231,95％CI:(-1.603,-0.859)]in broilers;adding Bacillus subtilis to the diet can significantly increase the overall ADG[SMD=2.582,95％CI:(2.147,3.017)]and ADFI[SMD=0.606,95％CI:(0.263,0.948)]of broilers at 1 to 42 days of age,and reduce the F/G[SMD=-1.841,95％CI:(-2.123,-1.559)];adding Bacillus subtilis to the diet could significantly increase the slaughter weight of broilers(42 days of age)[SMD=2.301,95％CI:(1.875,2.728)].The results of sub-group analysis showed that Bacillus licheniformis and Bacillus lipase producing bacteria had better growth pro-moting effects than Bacillus subtilis;the effects of Bacillus licheniformis on improving F/G in broilers is supe-rior to the other two types of Bacillus;Bacillus subtilis has the best effect in promoting the growth of Ross 308.Meta analysis shows that Bacillus can improve the growth performance of broiler chickens at different stages,and Bacillus has the best effect in promoting the growth of Ross 308;there are differences in the promoting effects of different Bacillus strains,with Bacillus licheniformis having the best promoting effect.[Chinese Journal of Animal Nutrition,2024,36(8):5353-5363]
万方数据
维普
