Mucin(Muc)2 is the main component of intestinal mucus barrier.Glycosylation modification is the decisive factor of Muc2,and intestinal symbiosis is an important factor affecting the degree of glycosylation.Glycosylation modification determines the conformational and physicochemical properties of Muc2,protects the integrity of Muc2,and affects the colonization of intestinal symbiotic bacteria,which in turn can regulate the glycosylation modification of Muc such as Muc2.This paper focuses on the interaction mechanism and nutri-tional regulation of intestinal symbiotic bacteria and Muc2 glycosylation modification,aiming to provide theo-retical basis for nutritional intervention and related studies of intestinal Muc2 glycosylation modification in pig-lets.[Chinese Journal of Animal Nutrition,2024,36(9):5523-5534]
维普
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