This experiment was conducted to investigate the effects of fumaric acid and cinnamaldehyde and their combination on growth performance,serum indices and intestine health of 817 broilers.A total of 600 1-day-old healthy 817 broilers were randomly divided into 4 groups with 10 replicates per group and 15 broilers per replicate.Broilers in the control group(CON group)were fed a basal diet,and those in the experimental groups were fed the basal diet supplemented with 600 mg/kg fumaric acid(FA group),400 mg/kg cinnamal-dehyde(CA group)and 600 mg/kg fumaric acid+400 mg/kg cinnamaldehyde(FC group),respectively.The experiment lasted for 42 days.The results show as follows:1)from 21 to 42 days of age,compared with CON group,the final body weight(FBW)and average daily gain(ADG)of broilers in FA and CA groups were significantly increased(P＜0.05),FBW and ADG in FC group were extremely significantly increased(P＜0.01),and the average daily feed intake(ADFI)in FA,CA and FC groups was significantly increased(P＜0.05);from 1 to 42 days of age,compared with CON group,ADG in FA and CA groups was signifi-cantly increased(P＜0.05),and ADG in FC group was extremely significantly increased(P＜0.01).2)Com-pared with CON group,the activities of serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)of broilers in CA and FC groups were significantly decreased(P＜0.05),and the activities of serum ALT and AST in FC group were significantly lower than those in CA group(P＜0.05).3)Compared with CON group,the serum immunoglobulin M(IgM)and glutathione(GSH)contents and superoxide dismutase(SOD)activity of broilers in all experimental groups were significantly increased(P＜0.05),while the serum malondialdehyde(MDA)content was significantly decreased(P＜0.05);among them,the serum MDA con-tent in FC group was significantly lower than that in FA and CA groups(P＜0.05),and the serum IgM and GSH contents and SOD activity in FC group were significantly higher than those in FA and CA groups(P＜0.05).4)At 21 and 42 days of age,compared with CON group,the villus height in duodenum and jejunum of broilers in CA and FC groups was significantly increased(P＜0.05).5)Compared with CON group,the Chao1 index of cecal microbiota of broilers in all experimental groups was significantly increased(P＜0.05),and the ACE index of cecal microbiota in CA and FC groups was significantly increased(P＜0.05).At the phylum level,the Bacteroidota relative abundance in cecum of broilers in all experimental groups was signifi-cantly increased(P＜0.05),and the Proteobacteria relative abundance in cecum was significantly decreased(P＜0.05);at the genus level,compared with CON group,the Lactobacillus relative abundance in cecum in all experimental groups was significantly increased(P＜0.05),and the Lactobacillus relative abundance in ce-cum in FC group was significantly higher than that in CA and FA groups(P＜0.05).In conclusion,dietary supplementation of fumaric acid or cinnamaldehyde alone or in combination can increase ADG and antioxidant capacity,increase serum IgM content,and improve cecal microbiota structure of broilers;dietary supplementa-tion of cinnamaldehyde alone and fumaric acid combined with cinnamaldehyde can also decrease the activities of serum ALT and AST,and improve the intestinal tissue morphology;compared with the single supplementa-tion,the combination of fumaric acid and cinnamaldehyde is more effective.[Chinese Journal of Animal Nutrition 2024,36(10):6345-6357]
关键词
富马酸/肉桂醛/肉鸡/生长性能/血清指标/肠道健康
Key words
fumaric acid/cinnamaldehyde/broilers/growth performance/serum indices/intestine health
维普
万方数据