Metabolite Changes,Candidate Genes and Related Metabolic Pathways of Ketosis in Dairy Cows
Ketosis as a common metabolic disease can reduce the milk yield and reproductive performance of dairy cows,increase the risk of other perinatal diseases,and cause significant economic losses to the dairy in-dustry.Ketone body is an important metabolic signaling mediator of ketone sickness in dairy cows.The occur-rence of ketosis involves many metabolic pathways and genomic changes,including lipid metabolism,amino acid metabolism and sugar metabolism,but the correlation between metabolite content changes and candidate genes in ketosis cows is lacking.This review summarizes the changes of ketone body metabolism in dairy cows,and the screening of ketosis targeted genes,combining candidate genes and metabolic pathway analysis can help to elucidate the potential molecular mechanism of ketosis in dairy cows,and provide technical support for the rapid and accurate diagnosis of ketosis in dairy cows in production practice.[Chinese Journal of Animal Nutrition,2024,36(11):6864-6871]
万方数据
维普
