The wide application of antibiotics has brought great changes to human health,but now the abuse of antibiotics has become a major crisis of human health,and it is urgent to find new drugs to replace traditional antibiotics.Insect antimicrobial peptides is a kind of small molecule polypeptide produced by insects to resist the attack of pathogenic bacteria.Insect antimicrobial peptides have broad spectrum antibacterial activity,and their killing effect on some drug-resistant pathogens has attracted more attention.This review mainly summarizes the structural characteristics,mechanism of action,and biological functions of antimicrobial peptides from black soldier fly,and analyzed the potential of antimicrobial peptides from black soldier fly for the development of new drugs,which provided a reference for the research of antimicrobial peptides from black soldier fly,and provided a new direction for the development of new drugs and the reduction of the abuse of antibiotics.[Chi-nese Journal of Animal Nutrition,2024,36(11):6929-6941]
关键词
黑水虻/抗菌肽/抑菌/抗肿瘤/抗病毒/作用机理
Key words
black soldier fly/antimicrobial peptides/bacteriostasis/anti-tumor/anti-viral/action mechanism