Difference Analysis of Slaughter Performance,Plasma Biochemical Indices and Plasma Metabolome of Tan Sheep with High and Low Feed Conversion Ratios
Feed conversion ratio(FCR)measures the feed utilization efficiency in Tan sheep.This study aimed to analyze the differences in slaughter performance,plasma biochemical indices and plasma metabolome be-tween high and low FCR Tan sheep,providing a reference for evaluating the production efficiency of Tan sheep by calculating FCR.A total of 156 three-month-old male Tan sheep with similar birth dates,good growth conditions and similar body weight were selected for uniform feeding and management.The experiment lasted 75 days,comprising a 15-day transition period,a 10-day pre-feeding period,and a 50-day normal feeding pe-riod.Based on FCR level,Tan sheep were divided into a high FCR group(FCR＞mean+0.5 SD)and a low FCR group(FCR＜mean-0.5 SD).Differences in slaughter performance,plasma biochemical indexes and plasma metabolome of Tan sheep between the high FCR group and low FCR group were compared and ana-lyzed.The results showed as follows:1)the head and hoof weights of Tan sheep in the high FCR group were extremely significantly higher than those in the low FCR group(P＜0.01),and the slaughter rate,carcass weight,and heart and spleen weights of Tan sheep in the high FCR group were significantly higher than those in the low FCR group(P＜0.05).2)The plasma total antioxidant capacity(T-AOC)of Tan sheep in the high FCR group was significantly higher than that in the low FCR group(P＜0.01),and the superoxide dismutase(SOD)activity,reduced glutathione(GSH)and interleukin-10(IL-10)contents in plasma of Tan sheep in the high FCR group were significantly higher than those in the low FCR group(P≤0.05).Additionally,the contents of malondialdehyde(MDA),interleukin-2(IL-2)and albumin(ALB)in plasma of Tan sheep in the high FCR group were extremely significantly lower than those in the lower FCR group(P＜0.01),and the total cholesterol(TC)content in plasma of Tan sheep in the high FCR group was significantly lower than that in the low FCR group(P＜0.05).3)Differential metabolites with area under curve(AUC)＞0.8,including 1,2-docosahexaenoic acid-sn-glycerol-3-phosphate choline,2-chloroepoxyethane,and N-lauroyl-D-erythro-phosphocholine,were upregulated in the plasma of Tan sheep in the high FCR group compared with the low FCR group;differential metabolites between the high FCR group and low FCR group were mainly enriched in oxidative phosphorylation,parathyroid hormone synthesis,secretion and action,epithelial cell signaling path-ways in Helicobacter pylori infection,and sphingolipid,etc.pathways.It can be seen that the FCR of Tan sheep is closely related to energy metabolism,calcium and phosphorus metabolism,etc.Compared with low FCR Tan sheep,high FCR Tan sheep exhibit stronger antioxidant and anti-inflammatory capabilities,less fat accumulation,higher slaughter rate and carcass weight after slaughter,and larger heart and spleen weights,but relatively lower feed utilization efficiency.[Chinese Journal of Animal Nutrition,2024,36(12):7879-7890]
Tan sheepfeed conversion ratioslaughter performanceplasma biochemical indicesdifferential metabolites
万方数据
维普
