Effects of Combination of Curcumin and Vitamin E on Nutrient Apparent Digestibility,Serum Biochemical Indices and Lipid Metabolism of Beagle Dogs
The aim of this study was to investigate the effects of combination of curcumin and vitamin E on the apparent digestibility of nutrients,serum biochemical indices and lipid metabolism of Beagle dogs.Eighteen Beagle dogs about 12 months old were randomly divided into three groups(n=6),and they were fed basal di-et(control group),basal diet+50 mg/kg curcumin+100 mg/kg vitamin E(Cur-50 group),basal diet+100 mg/kg curcumin+100 mg/kg vitamin E(Cur-100 group),respectively.After 30 days,the apparent di-gestibility of nutrients,serum biochemical and lipid metabolism indices were determined,and fecal scores were performed.The results showed that,compared with the control group,the apparent digestibility of ether extract in Cur-100 group was significantly increased(P＜0.05),serum total protein(TP)content and fecal secretory immunoglobulin A(sIgA)contents were significantly increased(P＜0.05),and serum urea nitrogen(UN)content and fecal scores on days 15 and 30 were significantly decreased(P＜0.05);fecal sIgA content in Cur-50 group was significantly increased(P＜0.05).In terms of lipid metabolism,the contents of serum total cho-lesterol(TC),triglyceride(TG)and low-density lipoprotein(LDL-C)in Cur-100 group were significantly decreased(P＜0.05),while the activity of serum lipoprotein lipase(LPL)was significantly increased com-pared with the control group(P＜0.05);serum TC content in Cur-50 group was significantly decreased(P＜0.05),and the activity of serum LPL was significantly increased compared with the control group(P＜0.05).In summary,curcumin combined with vitamin E can improve the apparent digestibility of ether extract,pro-mote nitrogen metabolism,improve fecal status,improve the body's immunity,promote lipid metabolism and reduce the level of blood lipids in Beagle dogs.[Chinese Journal of Animal Nutrition,2024,36(12):7986-7994]
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维普
