摘要
手性的研究在化学特别在有机化学领域具有非常重要的理论意义和应用前景,随着科学技术的发展及人们认识的提高,新概念新技术层出不穷.固有手性是无垂直对称面的曲面引起的手性,它不同于一般的中心手性、轴手性、面手性、螺旋手性,具有特殊的立体化学和广泛的应用前景.本文综述了天然固有手性化合物,合成的固有手性杯芳烃、柱芳烃、环三藜芦烃、三苯三戊并烯、马鞍状八元环、素馨烯、笼状化合物等的结构特点、合成及拆分,并展望了该领域的未来发展方向和新机遇.
Abstract
Chirality research holds paramount theoretical significance and practical prospects in the field of organic chemistry.With the advancement of science and technology and the deepening of our understanding,a plethora of new concepts and techniques continue to emerge.Inherent chirality arises from the introduction of a curvature in an ideal planar structure that is devoid of perpendicular symmetry planes in its bidimensional representation,distinguished from conventional central,axial,planar,and helical chirality.It possesses unique stereochemistry and offers extensive application prospects.This review focuses on the structural characteristics,synthesis,and separation of naturally occurring inherent chiral compounds,synthetically derived chiral calixarenes,pillararenes,cyclotriveratrylenes,tribenzotriquinacenes,saddle-shaped octatomic rings,sumanenes,and cage compounds.Furthermore,it sheds light on future developmental directions and new opportunities in this domain.
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