摘要
分析化学中,定量分析方法的性能评价参数包括:加标回收率、相对标准偏差、校准曲线及其相关系数、线性范围、误差棒、检测限、灵敏度、选择性、稳定性等,深刻理解以上参数的含义并熟练运用是分析化学工作者的基本素养.然而,对大多数高年级本科生和硕士研究生问卷调查发现,掌握常用分析参数用法的学生不足半数,并且无法区分含义相近参数.这是由于目前的教材仅仅介绍分析参数的基本概念,缺乏其实际应用的举例,而且尚无文献以举例的方式系统完整地介绍分析参数应用方式.本文精选分析化学中引用率最高的期刊Analytical Chemistry中多篇前沿文章,通过具体实例生动透彻地讲解各个评价参数的标准应用方式,代替以往单一的理论介绍.本工作旨在引导学生深刻理解基于评价参数直观的评价分析方法和分析结果的有效性,并且能够在以后的科研工作中熟练使用、准确表达,以期为改进更具科学实用的评价参数教学内容提供参考.
Abstract
In analytical chemistry,performance evaluation parameters for quantitative analysis methods include the spiked recovery,relative standard deviation,calibration curve and its correlation coefficient,linear range,error bar,limit of detection,sensitivity,selectivity,stability,etc.A deep understanding and proficient application of the above parameters are fundamental competencies for professionals in analytical chemistry.However,less than half of the students possess an adequate grasp of these common evaluation parameters,and could not distinguish parameters with similar meanings from the questionnaire survey for most senior undergraduates and postgraduate students.This deficiency is attributed to existing textbooks that merely introduce basic concepts of these parameters without illustrating their practical applications.Additionally,no comprehensive literature has systematically presented examples of how to apply these parameters.This paper carefully selects multiple cutting-edge articles from the highly-cited journal Analytical Chemistry,to vividly and thoroughly explain the standard applications of each evaluation parameters,replacing the previous one-dimensional theoretical descriptions.The goal of this work is to guide students in gaining a deep,intuitive understanding of how to effectively evaluate analytical methods and results based on these parameters,and to enable proficient and accurate expression in future scientific research.This paper aims to serve as a reference for improving the scientific and practical aspects of teaching evaluation parameters.
基金项目
河南省高等教育教学改革研究与实践项目(2021SJGLX127Y)
维普
万方数据